Diego Aceña Moreno was born in Madrid and began his flute studies at the age of seven at the Amaniel Conservatory of Music in Madrid.

After graduating from the Conservatorio Superior de Música de Aragón, he studied at the Royal College of Music in London with Jaime Martín, Sue Thomas, Chris Green and Stewart Mcilwham, receiving scholarships from the Community of Madrid and the Leverhulme Orchestra Mentroship and completing his Master in Orchestral Performance, finishing in 2013 with Distinction and winning the RCM first prize for flute.

He gained orchestral experience being a member of the prestigious Gustav Mahler Jugendorchester, Gustav Mahler Akademie and Schleswig-Holstein Musik Festival. Before completing his studies, he won the position of academician at the London Philharmonic Orchestra (2013/2014) and then at the Staatskapelle Dresden (2014-2016), where Sabine Kittel was his mentor and also receiving classes from Rozalia Szabo. Diego Aceña Moreno has been Flute Co Soloist at the Staatstheater Kassel since 2016, and regularly collaborates with orchestras such as the Mahler Chamber Orchestra, Staatskapelle Dresden, the National Orchestra of Spain, the Frankfurt Opera, the Barcelona Symphony Orchestra, the Orquesta Musicaeterna, the Orquesta de the Valencian Community, Essen Philharmonic and London Philharmonic Orchestra. Numerous concert tours have taken him to Europe, Asia and South America, working with conductors such as Christian Thielemann, Andris Nelsons, Herbert Blomstedt, Paavo Järvi, Theodor Currentzis, Daniel Harding and Yannick Nézet-Séguin to name a few.

He is very active in the field of chamber music, participating with different ensembles in festivals throughout Europe, and recording albums with groups such as Moonwinds or Ensemble Mini, with which he received the 2021 Opus Klassik Chamber Music Award for the recording of the Mahler disc 10 for chamber ensemble. He has won numerous awards and has performed as a soloist at London's Wigmore Hall, in Bolzano with the Gustav Mahler Academy and with the Staatsorcheter Kassel. Diego Aceña Moreno has taught courses at the Orchesterzentrum NRW in Dortmund as a professor at the Mahler Chamber Academy and has also collaborated as a professor with the Young Philharmonic of Colombia.